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Angiotensin Ⅱ in coronary heart disease and inflammatory factors in


[ 6-91 , suggesting that CHD patients with renin-angiotensin system is activated in vivo and the presence of chronic inflammation ,[link widoczny dla zalogowanych], which further confirms the renin- angiotensin system and chronic inflammation in the occurrence of atherosclerosis , development plays an important role. The results also show that , CHD AngII and the inflammatory cytokines in serum IL- 6, TNF-d and hs-CRP were significantly correlated , suggesting that Ang Ⅱ and influence of plaque instability inflammatory cytokines an association between , suggesting that Two may work together to promote coronary artery disease occurrence and development . The reason may be the trigger of myocardial ischemia and cardiac renin -angiotensin system activation,[link widoczny dla zalogowanych], while the cycle and the increase in the heart of local AnglI passed the pro-inflammatory ,[link widoczny dla zalogowanych], and promote macrophage uptake of oxidized low density lipoprotein, endothelial cells and a series of pathological features Further increase the role of coronary artery disease and myocardial ischemia attack , thus creating a vicious cycle in which continuous progress of stenosis . Since this study is cross-sectional study , and the study sample was smaller, and its conclusions remain to be further large-scale, prospective students basic and clinical research l confirmed. In conclusion , CHD patients in vivo angiotensin Ⅱ and is closely related to inflammatory factors may participate in the occurrence of CHD development . 【
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